UBP301 (hydrochloride)
UBP301 hydrochloride is a potent and selective antagonist of kainate receptor with IC50 and KD of 164 μM and 5.94 μM, respectively. UBP301 hydrochloride has ～30-fold selectivity of kainate receptor over AMPA receptor. UBP301 hydrochloride is the derivative of willardiine[1].
Product Specifications
UNSPSC
12352005
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ubp301-hydrochloride.html
Purity
97.45
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N(C=C(I)C1=O)C[C@H](N)C(O)=O)N1CC2=CC=C(C(O)=O)C=C2.[H]Cl
Molecular Formula
C15H15ClIN3O6
Molecular Weight
495.65
References & Citations
[1]More JC, et al. Structural requirements for novel willardiine derivatives acting as AMPA and kainate receptor antagonists. Br J Pharmacol. 2003;138 (6) :1093-1100.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
K2554805 3x 1.0 µg
TTTY8 sgRNA CRISPR/Cas9 All-in-One Lentivector set (Human)
Sign In for Pricing
View Details 215211 100 µg
WIPI2 (WD Repeat Domain, Phosphoinositide Interacting 2) discontinued
Sign In for Pricing
View Details LV709016 1.0 µg DNA
CS Lentiviral Vector (Human) (EF1a) (pLenti-GIII-EF1a)
Sign In for Pricing
View Details GSK3B-2382R 50 µg
Recombinant Rat GSK3B Protein, His (Fc)-Avi-tagged
Sign In for Pricing
View Details