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RH01617

RH01617 is a Kv1.5. potassium channel and MMP-13 inhibitor. RH01617 can be used for research of atrial fibrillation[1][2].

Product Specifications

CAS Number

[302333-18-2]

UNSPSC

12352005

Target

MMP; Potassium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/rh01617.html

Smiles

O=C(OC)[C@H](CC1=CNC2=C1C=CC=C2)NS(=O)(C3=CC=C(OCCCC)C=C3)=O

Molecular Formula

C22H26N2O5S

Molecular Weight

430.52

References & Citations

[1]Guo X, et al. Design and bio-evaluation of indole derivatives as potent Kv1.5 inhibitors. Bioorg Med Chem. 2013 Nov 1;21 (21) :6466-76.|[2]Leung JM, et al. Identification of T. gondii myosin light chain-1 as a direct target of TachypleginA-2, a small-molecule inhibitor of parasite motility and invasion. PLoS One. 2014 Jun 3;9 (6) :e98056.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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