EZH2-IN-2
Product Specifications
UNSPSC Description
EZH2-IN-2 is a EZH2 inhibitor extracted from patent WO2018133795A1, Compound Example 69, with an IC50 of 64 nM. EZH2-IN-2 can be used for the research of cancer or precancerous condition related to EZH2 activity[1].
Target Antigen
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ezh2-in-2.html
Purity
99.60
Solubility
DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
O=C(NCC1=C(C)C=C(C)NC1=O)C2=CC(C3=CC=C(N4CCN(CC5CC5)CC4)N=C3C)=CC(N(C(C6CC6)=O)CC)=C2C
Molecular Weight
610.79
References & Citations
[1]LIU, Qing Song, et al. Ezh2 inhibitor and use thereof. WO2018133795A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-A0298/EZH2-IN-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-A0298/EZH2-IN-2-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2238821-31-1
Available Sizes
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