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SMIFH2

SMIFH2 is a formin specific inhibitor. SMIFH2 inhibits actin polymerization by Formins and affects the actin cytoskeleton[1].

Product Specifications

CAS Number

340316-62-3

UNSPSC

12352005

Hazard Statement

H315, H319

Target

Arp2/3 Complex

Type

Reference compound

Related Pathways

Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/smifh2.html

Concentration

10mM

Purity

99.08

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(/C(C(N1C2=CC=CC(Br)=C2)=O)=C\C3=CC=CO3)NC1=S

Molecular Formula

C15H9BrN2O3S

Molecular Weight

377.21

Precautions

H315, H319

References & Citations

[1]Tadamoto Isogai, et al. SMIFH2 has effects on Formins and p53 that perturb the cell cytoskeleton. Sci Rep. 2015 Apr 30;5:9802.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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