SMIFH2
SMIFH2 is a formin specific inhibitor. SMIFH2 inhibits actin polymerization by Formins and affects the actin cytoskeleton[1].
Product Specifications
CAS Number
[340316-62-3]
UNSPSC
12352005
Hazard Statement
H315, H319
Target
Arp2/3 Complex
Type
Reference compound
Related Pathways
Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/smifh2.html
Concentration
10mM
Purity
99.08
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(/C(C(N1C2=CC=CC(Br)=C2)=O)=C\C3=CC=CO3)NC1=S
Molecular Formula
C15H9BrN2O3S
Molecular Weight
377.21
Precautions
H315, H319
References & Citations
[1]Tadamoto Isogai, et al. SMIFH2 has effects on Formins and p53 that perturb the cell cytoskeleton. Sci Rep. 2015 Apr 30;5:9802.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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