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(R) -Irsenontrine

(R) -Irsenontrine ((R) -E2027), the R-enantiomer of Irsenontrine , is a potent phosphodiesterase 9 (PDE9) inhibitor with an IC50 value of 0.041 μM. (R) -Irsenontrine can be used for the research of neurological diseases[1].

Product Specifications

CAS Number

1429509-81-8

Product Name Alternative

(R) -E2027

UNSPSC

12352005

Target

Phosphodiesterase (PDE)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/r-irsenontrine.html

Purity

99.00

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

O=C1C2=C(N([C@]3([H])CCOC3)N=C2)C4=CC=C(C5=C(C)C=NC(OC)=C5C)C=C4N1

Molecular Formula

C22H22N4O3

Molecular Weight

390.44

References & Citations

[1]Yoshihiko N, et, al. Pyrazoloquinoline derivative. WO2013051639A1.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

PDE9

Available Sizes

Frequently Asked Questions

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