(R) -Irsenontrine
(R) -Irsenontrine ((R) -E2027), the R-enantiomer of Irsenontrine , is a potent phosphodiesterase 9 (PDE9) inhibitor with an IC50 value of 0.041 μM. (R) -Irsenontrine can be used for the research of neurological diseases[1].
Product Specifications
CAS Number
1429509-81-8
Product Name Alternative
(R) -E2027
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/r-irsenontrine.html
Purity
99.00
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C1C2=C(N([C@]3([H])CCOC3)N=C2)C4=CC=C(C5=C(C)C=NC(OC)=C5C)C=C4N1
Molecular Formula
C22H22N4O3
Molecular Weight
390.44
References & Citations
[1]Yoshihiko N, et, al. Pyrazoloquinoline derivative. WO2013051639A1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE9
Available Sizes
Frequently Asked Questions
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