(R) -Irsenontrine
(R) -Irsenontrine ((R) -E2027), the R-enantiomer of Irsenontrine , is a potent phosphodiesterase 9 (PDE9) inhibitor with an IC50 value of 0.041 μM. (R) -Irsenontrine can be used for the research of neurological diseases[1].
Product Specifications
CAS Number
1429509-81-8
Product Name Alternative
(R) -E2027
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/r-irsenontrine.html
Purity
99.00
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=C1C2=C(N([C@]3([H])CCOC3)N=C2)C4=CC=C(C5=C(C)C=NC(OC)=C5C)C=C4N1
Molecular Formula
C22H22N4O3
Molecular Weight
390.44
References & Citations
[1]Yoshihiko N, et, al. Pyrazoloquinoline derivative. WO2013051639A1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE9
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Sodium Potassium ATPase (ATP1A1) (NM_000701) Human Over-expression Lysate
C19orf15 (CATSPERG) Human Gene Knockout Kit (CRISPR)
