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Azido-PEG2-azide

Product Specifications

UNSPSC Description

Azido-PEG2-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

Target Antigen

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/azido-peg2-azide.html

Purity

98.11

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

[N-]=[N+]=NCCOCCOCCN=[N+]=[N-]

Molecular Weight

200.20

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-W044155/Azido-PEG2-azide-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-W044155/Azido-PEG2-azide-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

59559-06-7

Available Sizes

Curated Selection

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