M-Carboxycinnamic acid bishydroxamide
M-Carboxycinnamic acid bishydroxamide is a potent HDAC inhibitor, exhibiting ID50 values of 10 and 70 nM in vitro for HDAC1 and HDAC3, respectively[1]. m-Carboxycinnamic acid bishydroxamide also induces apoptosis and suppresses tumor growth[2].
Product Specifications
CAS Number
[174664-65-4]
Product Name Alternative
CBHA
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/m-carboxycinnamic-acid-bishydroxamide.html
Purity
98.0
Solubility
DMSO : 25 mg/mL (ultrasonic; warming)
Smiles
O=C(C1=CC=CC(/C=C/C(NO)=O)=C1)NO
Molecular Formula
C10H10N2O4
Molecular Weight
222.20
Precautions
H315, H319, H335
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W014004/m-Carboxycinnamic-acid-bishydroxamide-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W014004/m-Carboxycinnamic-acid-bishydroxamide-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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