2-Deoxy-D-glucose-13C-1
2-Deoxy-D-glucose-13C-1 is the 13C labeled 2-Deoxy-D-glucose. 2-Deoxy-D-glucose is a glucose analog that acts as a competitive inhibitor of glucose metabolism, inhibiting glycolysis via its actions on hexokinase[1][2].
Product Specifications
CAS Number
119897-50-6
Product Name Alternative
2-DG-13C-1; 2-Deoxy-D-arabino-hexose-13C-1; D-Arabino-2-deoxyhexose-13C-1
UNSPSC
12352211
Target
Apoptosis; Hexokinase; HSV; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Apoptosis; Metabolic Enzyme/Protease; Others
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-deoxy-d-glucose-13c-1.html
Solubility
10 mM in DMSO
Smiles
O=CC[C@@H](O)[C@H](O)[C@H](O)[13CH2]O
Molecular Formula
C5 13CH12O5
Molecular Weight
165.15
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Zhu Z, et al. 2-Deoxyglucose as an energy restriction mimetic agent: effects on mammary carcinogenesis and on mammary tumor cell growth in vitro. Cancer Res. 2005 Aug 1;65 (15) :7023-30.; Ueyama A, et al. Nonradioisotope assay of glucose uptake activity in r
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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