BuChE-IN-14
BuChE-IN-14 is a novel compound that selectively inhibits acetylcholinesterase (AChE) activity. BuChE-IN-14 showed a concentration-dependent inhibitory effect on AChE in rat brain in vitro experiments. BuChE-IN-14 can increase the extracellular acetylcholine (ACh) concentration in the rat hippocampus and striatum at a certain dose. BuChE-IN-14 may help improve memory impairment caused by cholinergic dysfunction[1].
Product Specifications
CAS Number
38455-99-1
UNSPSC
12352005
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/buche-in-14.html
Smiles
O=C(C1=CC(OC)=C(C(OC)=C1)OC)OCCN2CCN(CCCN3C4=C(SC5=CC(Cl)=CC=C53)C=CC=C4)CC2
Molecular Formula
C31H36ClN3O5S
Molecular Weight
598.15
References & Citations
[1]Effects of T-82, a new quinoline derivative, on cholinesterase activity and extracellular acetylcholine concentration in rat brain
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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