MSC-1186
Product Specifications
UNSPSC Description
MSC-1186 is a highly selective pan-SRPK inhibitor. MSC-1186 has activity for SRPK1, SRPK2 and SRPK3 with IC50 values of 2.7 nM, 81 nM and 0.6 nM, respectively. MSC-1186 can be used for the research of cancer[1].
Target Antigen
SRPK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/msc-1186.html
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
CS(=O)(N(C1=NC=CC=C1CNC2=NC(C3=NC4=C(F)C(Cl)=CC=C4N3)=NC=C2)C)=O
Molecular Weight
461.90
References & Citations
[1]Martin Schröder, et al. MSC-1186, a Highly Selective Pan-SRPK Inhibitor Based on an Exceptionally Decorated Benzimidazole-Pyrimidine Core. J Med Chem. 2022 Dec 14.
Shipping Conditions
Blue Ice
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-148518/MSC-1186-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-148518/MSC-1186-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2871698-23-4
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS7168256 Inquire
Rabbit anti-Saccharomyces cerevisiae (strain YJM789)(Baker's yeast) ATG14 Polyclonal Antibody
Ask
View Details 
