MSC-1186
MSC-1186, a chemical probe, is a highly selective pan-SRPK inhibitor. MSC-1186 has activity for SRPK1, SRPK2 and SRPK3 with IC50 values of 2.7 nM, 81 nM and 0.6 nM, respectively. MSC-1186 can be used for the research of cancer[1].
Product Specifications
CAS Number
[2871698-23-4]
UNSPSC
12352005
Target
SRPK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/msc-1186.html
Concentration
10mM
Purity
98.95
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
CS(=O)(N(C1=NC=CC=C1CNC2=NC(C3=NC4=C(F)C(Cl)=CC=C4N3)=NC=C2)C)=O
Molecular Formula
C19H17ClFN7O2S
Molecular Weight
461.90
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-148518/MSC-1186-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-148518/MSC-1186-SDS-MedChemExpress.pdf
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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