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MDM2-IN-26

MDM2-IN-26 (compound A3) is an MDM2 inhibitor that can activate the tumor suppressor function of p53 by blocking the interaction between MDM2 and p53 (MDM2 is the main negative regulator of p53) . MDM2-IN-26 can be used for cancer research[1].

Product Specifications

CAS Number

1818393-11-1

UNSPSC

12352005

Target

MDM-2/p53

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mdm2-in-26.html

Solubility

10 mM in DMSO

Smiles

OC(C12CCC(CC2)(NC([C@H]3[C@H](C4=CC=CC(Cl)=C4F)[C@@]5(C(C=CC(Cl)=C6)=C6NC5=O)C7(CCC(F)(F)CC7)N3)=O)CC1)=O

Molecular Formula

C32H32Cl2F3N3O4

Molecular Weight

650.52

References & Citations

[1]Yifan Zhai, et al. MDM2 inhibitor and a platinum compound for cancer treatment. Patent US11850239B2.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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