Pomalidomide 4'-alkylC5-acid
Pomalidomide 4'-alkylC5-acid (Example 3) is an E3 ligase ligand-linker conjugate containing a Pomalidomide (HY-10984) based cereblon (CRBN) ligand and a linker. Pomalidomide 4'-alkylC5-acid can be used in the synthesis of PROTAC[1].
Product Specifications
CAS Number
[2225940-49-6]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pomalidomide-4-alkylc5-acid.html
Purity
98.78
Solubility
DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(O)CCCCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O
Molecular Formula
C19H21N3O6
Molecular Weight
387.39
Precautions
H302, H315, H319, H335
References & Citations
[1]Jian Jin, et al. Compositions and methods for treating cdk4/6-mediated cancer. Patent WO2018106870A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Available Sizes
Explore Other Products
Browse additional items from our catalog
SLC20A1P1 sgRNA CRISPR Lentivector (Human) (Target 3)
Integrin αX Lentiviral Activation Particles (h)