Netilmicin (sulfate)

Netilmicin (Sch 20569) sulfate is a broad-spectrum semisynthetic aminoglycoside antibiotic. Netilmicin sulfate exhibits antibacterial activity against aminoglycoside-susceptible gram-negative strains and aminoglycoside-resistant strain, such as Escherichia coli, Pseudomonas aeruginosa, Proteus, Staphylococcus aureus, Streptococcus, Serratia, and Enterobacter, with MIC of 0.125-8 μg/mL[1].

Product Specifications

CAS Number

[56391-57-2]

Product Name Alternative

SCH-20569 (sulfate)

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H332, H335, H350, H360

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Netilmicin-sulfate.html

Purity

98.0

Solubility

DMSO : < 1 mg/mL|H2O : 100 mg/mL (ultrasonic)

Smiles

NCC1=CC[C@@H](N)[C@](O[C@@H]2[C@@H](N)C[C@@H](NCC)[C@H](O[C@@]3([H])OC[C@](C)(O)[C@H](NC)[C@H]3O)[C@H]2O)([H])O1.[2.5H2SO4]

Molecular Formula

C21H41N5O7.5/2H2SO4

Molecular Weight

720.78

Precautions

H302, H315, H319, H332, H335, H350, H360

References & Citations

[1]Miller GH, et al., Biological activity of netilmicin, a broad-spectrum semisynthetic aminoglycoside antibiotic. Antimicrob Agents Chemother. 1976 Nov;10 (5) :827-36.