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IACS-8968 (S-enantiomer)

Selected Variant

HY-112164B-01

Size: 5 mg

IACS-8968 (S-enantiomer) is the S-enantiomer of IACS-8968. IACS-8968 is a dual IDO and TDO inhibitor, with pIC50s of 6.43 for IDO and <5 for TDO, respectively.

Product Specifications

CAS Number

2239305-70-3

Product Name Alternative

IDO/TDO Inhibitor (S-enantiomer)

UNSPSC

12352005

Target

Indoleamine 2,3-Dioxygenase (IDO)

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/IDO/TDO_Inhibitor_S-enantiomer.html

Concentration

10mM

Purity

98.43

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(N1)N[C@@]2(C(C)(C)CN(C3=CC(C(F)(F)F)=CC4=CN=CN34)CC2)C1=O

Molecular Formula

C17H18F3N5O2

Molecular Weight

381.35

References & Citations

[1]ARYL SULFONOHYDRAZIDES. WO 2017189386 A1.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Price

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