MCC

MCC is non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as MCC-DM1[1].

Product Specifications

CAS Number

[104676-09-7]

UNSPSC

12352203

Hazard Statement

H302, H315, H319, H335

Target

ADC Linker

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mcc.html

Purity

95.0

Solubility

10 mM in DMSO

Smiles

O=C(C=CC1=O)N1CC2CCC(C(N)=O)CC2

Molecular Formula

C12H16N2O3

Molecular Weight

236.27

Precautions

H302, H315, H319, H335

References & Citations

[1]Polson AG, et al. Anti-CD22-MCC-DM1: an antibody-drug conjugate with a stable linker for the treatment of non-Hodgkin's lymphoma. Leukemia. 2010;24 (9) :1566-1573.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, stored under nitrogen)

Scientific Category

ADC Related

Clinical Information

Phase 2

Available Sizes

Curated Selection

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