MCC
MCC is non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs), such as MCC-DM1[1].
Product Specifications
CAS Number
[104676-09-7]
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mcc.html
Purity
95.0
Solubility
10 mM in DMSO
Smiles
O=C(C=CC1=O)N1CC2CCC(C(N)=O)CC2
Molecular Formula
C12H16N2O3
Molecular Weight
236.27
Precautions
H302, H315, H319, H335
References & Citations
[1]Polson AG, et al. Anti-CD22-MCC-DM1: an antibody-drug conjugate with a stable linker for the treatment of non-Hodgkin's lymphoma. Leukemia. 2010;24 (9) :1566-1573.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, stored under nitrogen)
Scientific Category
ADC Related
Clinical Information
Phase 2
Available Sizes
Curated Selection
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