Olinvacimab

Olinvacimab (TTAC-0001) is a fully human anti-VEGFR2 monoclonal antibody. Olinvacimab inhibits VEGF binds to KDR with a Kd value of 0.23 nM. Olinvacimab has antiangiogenic activity. Olinvacimab can be used for the research of recurrent glioblastoma and breast cancer[1].

Product Specifications

CAS Number

[2095504-49-5]

Product Name Alternative

TTAC-0001

UNSPSC

12352203

Target

VEGFR

Type

Inhibitory Antibodies

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/olinvacimab.html

Purity

95.00

Solubility

10 mM in DMSO

Smiles

[Olinvacimab]

Molecular Weight

(148.16 kDa)

References & Citations

[1]Lee WS, et al. TTAC-0001, a human monoclonal antibody targeting VEGFR-2/KDR, blocks tumor angiogenesis. MAbs. 2015;7 (5) :957-68.

Shipping Conditions

Dry Ice

Storage Conditions

Store at -80°C for 2 years

Scientific Category

Inhibitory Antibodies

Clinical Information

Phase 2

Available Sizes

Curated Selection

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