DMT1 blocker 1
Product Specifications
UNSPSC Description
DMT1 blocker 1 (compound 6f) is a blocker of divalent metal transporter 1 (DMT1) with an IC50 of 0.64 μM, is expected to block iron uptake by enterocytes in vivo[1].
Target Antigen
Ferroportin
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/dmt1-blocker-1.html
Purity
99.79
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
OC1=C(C(NC2=CC=CC=C2)=O)C(C)=NN1C3=NC=CC=C3
Molecular Weight
294.31
References & Citations
[1]Cadieux JA, et al. Synthesis and biological evaluation of substituted pyrazoles as blockers of divalent metal transporter 1 (DMT1). Bioorg Med Chem Lett. 2012 Jan 1;22(1):90-5.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-126301/DMT1-blocker-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-126301/DMT1-blocker-1-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1354790-56-9
Available Sizes
Curated Selection
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