(16R) -Utidelone
(16R) -Utidelone ((16R) -Epothilone D) is the isomer of Utidelone , and can be used as an experimental control. Utidelone (KOS 862) is a potent microtubule stabilizer.
Product Specifications
Product Name Alternative
(16R) -Epothilone D; (16R) -UTD1; (16R) -KOS 862
UNSPSC
12352005
Target
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Neuroscience-Neuromodulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/16r-epothilone-d.html
Purity
95.11
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C[C@H](O)C1(C)C)O[C@@H](/C(C)=C/C2=CSC(C)=N2)C/C=C(C)\CCC[C@H](C)[C@H](O)[C@@H](C)C1=O
Molecular Formula
C27H41NO5S
Molecular Weight
491.68
References & Citations
[1]Brunden KR, et al. Epothilone D improves microtubule density, axonal integrity, and cognition in a transgenic mouse model of tauopathy.
 J Neurosci. 2010 Oct 13;30 (41) :13861-6.|[2]Konner J, et al. Phase I clinical, pharmacokinetic, and pharmacodynamic study of KOS-862 (Epothilone D) in patients with advanced solid tumors and lymphoma.
 Invest New Drugs. 2012 Dec;30 (6) :2294-302.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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