Amyloid-β-IN-1
Amyloid-β-IN-1 (compound 13) is a synthetic peptide containing the hydrophobic C-terminal region "VVIA-NH2" and its reverse sequence "AIVV-NH2" of Aβ42, which is an Aβ inhibitor. Amyloid-β-IN-1 can inhibit Aβ aggregation and has neuroprotective effects[1].
Product Specifications
UNSPSC
12352211
Target
Amyloid-β
Type
Reference compound
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/amyloid-β-in-1.html
Smiles
N[C@@H](C)C(N[C@@H]([C@@H](C)CC)C(NC(C)(C)C(N[C@@H](C(C)C)C(N)=O)=O)=O)=O
Molecular Formula
C18H35N5O4
Molecular Weight
385.50
References & Citations
[1]Synthesis and mechanistic study of Aβ42 C-terminus domain derived tetrapeptides that inhibit Alzheimer’s Aβ-aggregation-induced neurotoxicity
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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