Amyloid-β-IN-1

Amyloid-β-IN-1 (compound 13) is a synthetic peptide containing the hydrophobic C-terminal region "VVIA-NH2" and its reverse sequence "AIVV-NH2" of Aβ42, which is an Aβ inhibitor. Amyloid-β-IN-1 can inhibit Aβ aggregation and has neuroprotective effects[1].

Product Specifications

UNSPSC

12352211

Target

Amyloid-β

Type

Reference compound

Related Pathways

Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/amyloid-β-in-1.html

Smiles

N[C@@H](C)C(N[C@@H]([C@@H](C)CC)C(NC(C)(C)C(N[C@@H](C(C)C)C(N)=O)=O)=O)=O

Molecular Formula

C18H35N5O4

Molecular Weight

385.50

References & Citations

[1]Synthesis and mechanistic study of Aβ42 C-terminus domain derived tetrapeptides that inhibit Alzheimer’s Aβ-aggregation-induced neurotoxicity

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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