Niraparib metabolite M1
Niraparib metabolite M1 is a metabolite of niraparib, and the latter one acts as a novel poly (ADP-Ribose) polymerase (PARP) inhibitor.
Product Specifications
CAS Number
1476777-06-6
Product Name Alternative
Niraparib carboxylic acid metabolite M1; M1 metabolite of niraparib
UNSPSC
12352005
Hazard Statement
H315, H319
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/Niraparib-metabolite-M1.html
Concentration
10mM
Purity
99.69
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(C1=CC=CC2=CN(C3=CC=C([C@H]4CNCCC4)C=C3)N=C12)O
Molecular Formula
C19H19N3O2
Molecular Weight
321.37
Precautions
H315, H319
References & Citations
[1]van Andel L, et al. Liquid chromatography-tandem mass spectrometry assay for the quantification of niraparib and its metabolite M1 in human plasma and urine. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Nov 19;1040:14-21
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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