Niraparib metabolite M1

Niraparib metabolite M1 is a metabolite of niraparib, and the latter one acts as a novel poly (ADP-Ribose) polymerase (PARP) inhibitor.

Product Specifications

CAS Number

[1476777-06-6]

Product Name Alternative

Niraparib carboxylic acid metabolite M1; M1 metabolite of niraparib

UNSPSC

12352005

Hazard Statement

H315, H319

Target

Drug Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/Niraparib-metabolite-M1.html

Concentration

10mM

Purity

99.69

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C(C1=CC=CC2=CN(C3=CC=C([C@H]4CNCCC4)C=C3)N=C12)O

Molecular Formula

C19H19N3O2

Molecular Weight

321.37

Precautions

H315, H319

References & Citations

[1]van Andel L, et al. Liquid chromatography-tandem mass spectrometry assay for the quantification of niraparib and its metabolite M1 in human plasma and urine. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Nov 19;1040:14-21

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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