GDP366

GDP366, a dual inhibitor of survivin and Op18, induces cell growth inhibition, cellular senescence and mitotic catastrophe in human cancer cells.

Product Specifications

CAS Number

[501698-03-9]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Survivin

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/GDP366.html

Purity

99.80

Solubility

DMSO : 62.5 mg/mL (ultrasonic)

Smiles

O=C(NC1=CC=CC(C)=C1)NC2=CC=C(C3=CSC4=NC=NC(N)=C43)C=C2

Molecular Formula

C20H17N5OS

Molecular Weight

375.45

Precautions

H302, H315, H319, H335

References & Citations

[1]Shi X, et al. GDP366, a novel small molecule dual inhibitor of survivin and Op18, induces cell growth inhibition, cellular senescence and mitotic catastrophe in human cancer cells. Cancer Biol Ther. 2010 Apr 15;9 (8) :640-50.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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