2,6-Dichloro-2',3',5'-triacetyl-purine riboside
2,6-Dichloro-2',3',5'-triacetyl-purine riboside is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
[3056-18-6]
Product Name Alternative
2,6-Dichloro-9- (2’,3’,5’-tri-O-acetyl-β-D-ribofuranosyl) purine
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-6-dichloro-2-3-5-triacetyl-purine-riboside.html
Purity
97.0
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
ClC1=NC(Cl)=NC2=C1N=CN2[C@@H]3O[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H]3OC(C)=O
Molecular Formula
C15H14Cl2N4O7
Molecular Weight
433.20
Precautions
H302, H315, H319, H335
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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