Alclofenac
Alclofenac (Allopydin) is a non-steroidal anti-inflammatory agent (NSAID) . Alclofenac is a prostaglandin H2 synthase inhibitor. Alclofenac can be used for rheumatoid arthritis, degenerative joint disease and ankylosing spondylitis research[1][2].
Product Specifications
CAS Number
[22131-79-9]
Product Name Alternative
Allopydin; W-7320
UNSPSC
12352005
Hazard Statement
H302
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/alclofenac.html
Purity
99.44
Solubility
DMSO : 16.67 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
C=CCOC1=C(Cl)C=C(CC(O)=O)C=C1
Molecular Formula
C11H11ClO3
Molecular Weight
226.66
Precautions
H302
References & Citations
[1]R N Brogden, et al. Alclofenac: a review of its pharmacological properties and therapeutic efficacy in rheumatoid arthritis and allied rheumatic disorders. Drugs. 1977 Oct;14 (4) :241-59. |[2]B S Selinsky, et al. Structural analysis of NSAID binding by prostaglandin H2 synthase: time-dependent and time-independent inhibitors elicit identical enzyme conformations. Biochemistry. 2001 May 1;40 (17) :5172-80.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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