Alclofenac

Alclofenac (Allopydin) is a non-steroidal anti-inflammatory agent (NSAID) . Alclofenac is a prostaglandin H2 synthase inhibitor. Alclofenac can be used for rheumatoid arthritis, degenerative joint disease and ankylosing spondylitis research[1][2].

Product Specifications

CAS Number

[22131-79-9]

Product Name Alternative

Allopydin; W-7320

UNSPSC

12352005

Hazard Statement

H302

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/alclofenac.html

Purity

99.44

Solubility

DMSO : 16.67 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

C=CCOC1=C(Cl)C=C(CC(O)=O)C=C1

Molecular Formula

C11H11ClO3

Molecular Weight

226.66

Precautions

H302

References & Citations

[1]R N Brogden, et al. Alclofenac: a review of its pharmacological properties and therapeutic efficacy in rheumatoid arthritis and allied rheumatic disorders. Drugs. 1977 Oct;14 (4) :241-59. |[2]B S Selinsky, et al. Structural analysis of NSAID binding by prostaglandin H2 synthase: time-dependent and time-independent inhibitors elicit identical enzyme conformations. Biochemistry. 2001 May 1;40 (17) :5172-80.