Antifolate C1
Antifolate C1 (AGF 94) is a GARFTase inhibitor. Antifolate C1 inhibits de novo purine biosynthesis. Antifolate C1 inhibits cell proliferation[1].
Product Specifications
CAS Number
136784-51-5
Product Name Alternative
AGF 94
UNSPSC
12352005
Target
Antifolate
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antifolate-c1.html
Smiles
O=C1C2=C(NC(N)=N1)NC(CCCC3=CC=C(C(N[C@H](C(O)=O)CCC(O)=O)=O)S3)=C2
Molecular Formula
C19H21N5O6S
Molecular Weight
447.46
References & Citations
[1]O'Connor C, et al. Folate transporter dynamics and therapy with classic and tumor-targeted antifolates. Sci Rep. 2021 Mar 18;11 (1) :6389.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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