L57
Product Specifications
UNSPSC Description
L57 exhibits high affinity to the low-density lipoprotein receptor-related protein 1 (LRP1) with Ki of 45 nM. L57 exhibits blood-brain barrier (BBB) permeability and plasma stability. L57 can be utilized as the carrier for CNS drug delivery[1].
Target Antigen
Others
Type
Peptides
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/l57.html
Smiles
O=C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N3[C@@H](CCC3)C(N[C@@H](CCCCN)C(N[C@@H](CC4=CNC=N4)C(N[C@@H](CC5=CC=CC=C5)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN)C(N[C@@H](CC6=CNC=N6)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC7=CC=CC=C7)C(N[C@@H](CC8=CC=C(C=C8)O)C(N[C@@H](CO)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(NCC(N[C@@H](CCCCN)C(N[C@@H](CC9=CNC=N9)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H]([C@H](O)C)N
Molecular Weight
2483.87
References & Citations
[1]Sakamoto K, et al., A novel LRP1-binding peptide L57 that crosses the blood brain barrier. Biochem Biophys Rep. 2017 Aug 12;12:135-139.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P10502/L57-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P10502/
Clinical Information
No Development Reported
CAS Number
2378836-93-0
Curated Selection
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