Tomeglovir

Tomeglovir is a potent anti-CMV agent, inhibiting processing of viral DNA-concatemers, with IC50s of 0.34 μM and 0.039 μM for HCMV and MCMV.

Product Specifications

CAS Number

[233254-24-5]

Product Name Alternative

BAY 38-4766

UNSPSC

12352005

Target

CMV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/Tomeglovir.html

Purity

99.71

Solubility

DMSO : ≥ 108 mg/mL

Smiles

CC(C)(CO)C(NC1=CC=C(NS(=O)(C2=C3C=CC=C(N(C)C)C3=CC=C2)=O)C=C1)=O

Molecular Formula

C23H27N3O4S

Molecular Weight

441.54

References & Citations

[1]Weber O, et al. Inhibition of murine cytomegalovirus and human cytomegalovirus by a novel non-nucleosidic compound in vivo. Antiviral Res. 2001 Mar;49 (3) :179-89.|[2]Reefschlaeger J, et al. Novel non-nucleoside inhibitors of cytomegaloviruses (BAY 38-4766) : in vitro and in vivo antiviral activity and mechanism of action. J Antimicrob Chemother. 2001 Dec;48 (6) :757-67.