Tomeglovir
Tomeglovir is a potent anti-CMV agent, inhibiting processing of viral DNA-concatemers, with IC50s of 0.34 μM and 0.039 μM for HCMV and MCMV.
Product Specifications
CAS Number
[233254-24-5]
Product Name Alternative
BAY 38-4766
UNSPSC
12352005
Target
CMV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/Tomeglovir.html
Purity
99.71
Solubility
DMSO : ≥ 108 mg/mL
Smiles
CC(C)(CO)C(NC1=CC=C(NS(=O)(C2=C3C=CC=C(N(C)C)C3=CC=C2)=O)C=C1)=O
Molecular Formula
C23H27N3O4S
Molecular Weight
441.54
References & Citations
[1]Weber O, et al. Inhibition of murine cytomegalovirus and human cytomegalovirus by a novel non-nucleosidic compound in vivo. Antiviral Res. 2001 Mar;49 (3) :179-89.|[2]Reefschlaeger J, et al. Novel non-nucleoside inhibitors of cytomegaloviruses (BAY 38-4766) : in vitro and in vivo antiviral activity and mechanism of action. J Antimicrob Chemother. 2001 Dec;48 (6) :757-67.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Curated Selection
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