Desmethyl ferroquine

Desmethyl ferroquine (SSR97213) is the active and major metabolite of Ferroquine. Ferroquine is an antimalarial. Desmethyl ferroquine shows significant activity against Chloroquine-susceptible and resistant P. falciparum strains[1].

Product Specifications

CAS Number

[903546-18-9]

Product Name Alternative

SSR97213

UNSPSC

12352005

Target

Drug Metabolite; Parasite

Type

Reference compound

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/desmethyl-ferroquine.html

Purity

98.02

Solubility

DMSO : 2.5 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL

Smiles

CNCC12=[CH]3[Fe+2]1456789([CH-]%10[CH]6=[CH]7[CH]8=[CH]9%10)[C-]2([CH]4=[CH]53)CNC%11=CC=NC%12=C%11C=CC(Cl)=C%12

Molecular Formula

C22H22ClFeN3

Molecular Weight

419.73

References & Citations

[1]Supan C, et al. Pharmacokinetics of ferroquine, a novel 4-aminoquinoline, in asymptomatic carriers of Plasmodium falciparum infections. Antimicrob Agents Chemother. 2012 Jun;56 (6) :3165-73.