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STING antagonist-1

STING antagonist-1 is an antagonist of STING with an IC50 of 3.8 nM. STING antagonist-1 can be used in the research of autoimmune diseases, inflammatory diseases, and others[1].

Product Specifications

CAS Number

3036981-21-9

UNSPSC

12352005

Target

STING

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/sting-antagonist-1.html

Purity

99.88

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

F[C@H](C1=CC=CC=C1)CN2N=C3C=CC=C(C4=C(C5CC5)N(C)C(C6=CC7=CN(C)N=C7N=C6CC)=N4)C3=C2

Molecular Formula

C31H30FN7

Molecular Weight

519.62

References & Citations

[1]Hoffmann M, et al., Heterocyclic compounds as sting antagonists. WO2024089155A1.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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