STING antagonist-1
STING antagonist-1 is an antagonist of STING with an IC50 of 3.8 nM. STING antagonist-1 can be used in the research of autoimmune diseases, inflammatory diseases, and others[1].
Product Specifications
CAS Number
[3036981-21-9]
UNSPSC
12352005
Target
STING
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sting-antagonist-1.html
Purity
99.88
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
F[C@H](C1=CC=CC=C1)CN2N=C3C=CC=C(C4=C(C5CC5)N(C)C(C6=CC7=CN(C)N=C7N=C6CC)=N4)C3=C2
Molecular Formula
C31H30FN7
Molecular Weight
519.62
References & Citations
[1]Hoffmann M, et al., Heterocyclic compounds as sting antagonists. WO2024089155A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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