Trecovirsen

Trecovirsen (GEM91) is a 25-mer antisense phosphorothioate oligonucleotide targeted at the gag site of the HIV gene.

Product Specifications

CAS Number

[153021-75-1]

Product Name Alternative

GEM91

UNSPSC

12352208

Target

HIV

Type

Oligonucleotides

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/trecovirsen.html

Purity

97.98

Solubility

H2O : 200 mg/mL (ultrasonic)

Smiles

[Trecovirsen]

Molecular Weight

7776.30

References & Citations

[1]Séréni D, Tubiana R, Lascoux C, et al. Pharmacokinetics and tolerability of intravenous trecovirsen (GEM 91), an antisense phosphorothioate oligonucleotide, in HIV-positive subjects. J Clin Pharmacol. 1999;39 (1) :47-54. |[2]Pedziwiatr-Werbicka E, Fuentes E, Dzmitruk V, et al. Novel 'Si-C' carbosilane dendrimers as carriers for anti-HIV nucleic acids: studies on complexation and interaction with blood cells. Colloids Surf B Biointerfaces. 2013;109:183-189.