Benzydamine (hydrochloride)

Benzydamine hydrochloride is an orally administered prostaglandin synthesis inhibitor that has anti-inflammatory, analgesic, antipyretic, and antibacterial properties. Benzydamine hydrochloride can inhibit TNF-α, stabilize cell membranes, and reduce oxidative stress within cells[1][2][3].

Product Specifications

CAS Number

[132-69-4]

UNSPSC

12352005

Hazard Statement

H302, H319

Target

Bacterial; PGE synthase; TNF Receptor

Type

Reference compound

Related Pathways

Anti-infection; Apoptosis; Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cancer

Assay Protocol

https://www.medchemexpress.com/Benzydamine-hydrochloride.html

Concentration

10mM

Purity

99.21

Solubility

H2O : ≥ 41 mg/mL

Smiles

CN(C)CCCOC1=NN(CC2=CC=CC=C2)C3=C1C=CC=C3.[H]Cl

Molecular Formula

C19H24ClN3O

Molecular Weight

345.87

Precautions

H302, H319

References & Citations

[1]Fanaki NH, et al. Antimicrobial activity of benzydamine, a non-steroid anti-inflammatory agent. J Chemother. 1992 Dec;4 (6) :347-52.|[2]Quane PA, Pharmacology of benzydamine. Inflammopharmacology. 1998;6 (2) :95-107|[3]R S Turnbull, et al. Benzydamine Hydrochloride (Tantum) in the management of oral inflammatory conditions. J Can Dent Assoc. 1995 Feb;61 (2) :127-34.