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Isatropolone A

Product Specifications

UNSPSC Description

Isatropolone A, a natural product containing a 1,5-diketone moiety, is reisolated from Streptomyces G?66. Isatropolone A shows potent activity against Leishmania donovani with an IC50 of 0.5 μM[1].

Target Antigen

Parasite

Type

Natural Products

Related Pathways

Anti-infection

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/isatropolone-a.html

Solubility

10 mM in DMSO

Smiles

O=C(C=C1C2=C3OC(C)=CC2=C(C1=O)C(CCC)=O)C4=C3O[C@]5([C@@]4([C@@H]([C@@H]([C@H](O5)C)OC)O)O)[H]

Molecular Weight

456.44

References & Citations

[1]Xiaofeng Cai, et al. Structure and Biosynthesis of Isatropolones, Bioactive Amine-Scavenging Fluorescent Natural Products from Streptomyces Gö66. Angew Chem Int Ed Engl. 2017 Apr 24;56(18):4945-4949.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-130993/Isatropolone-A-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-130993/

Clinical Information

No Development Reported

CAS Number

2097813-40-4

Available Sizes

Curated Selection

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