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Isatropolone A

Isatropolone A, a natural product containing a 1,5-diketone moiety, is reisolated from Streptomyces G 66. Isatropolone A shows potent activity against Leishmania donovani with an IC50 of 0.5 μM[1].

Product Specifications

CAS Number

[2097813-40-4]

UNSPSC

12352005

Target

Parasite

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/isatropolone-a.html

Solubility

10 mM in DMSO

Smiles

O=C(C=C1C2=C3OC(C)=CC2=C(C1=O)C(CCC)=O)C4=C3O[C@]5([C@@]4([C@@H]([C@@H]([C@H](O5)C)OC)O)O)[H]

Molecular Formula

C24H24O9

Molecular Weight

456.44

References & Citations

[1]Xiaofeng Cai, et al. Structure and Biosynthesis of Isatropolones, Bioactive Amine-Scavenging Fluorescent Natural Products from Streptomyces Gö66. Angew Chem Int Ed Engl. 2017 Apr 24;56 (18) :4945-4949.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

Leishmania

Available Sizes

Curated Selection

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