Octanoic acid

Octanoic acid (Caprylic acid) is an oily liquid with a slightly unpleasant rancid taste and used commercially in the production of esters used in perfumery and also in the manufacture of dyes. Octanoic acid is also a tremor-suppressing agent[1][2].

Product Specifications

CAS Number

[124-07-2]

Product Name Alternative

Caprylic acid

UNSPSC

12352211

Hazard Statement

H314, H412

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/1-Heptanecarboxylic_acid.html

Purity

99.85

Solubility

DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CCCCCCCC(O)=O

Molecular Formula

C8H16O2

Molecular Weight

144.21

Precautions

H314, H412

References & Citations

[1]Nahab FB, et al. Octanoic acid suppresses harmaline-induced tremor in mouse model of essential tremor. Neurotherapeutics. 2012 Jul;9 (3) :635-8.|[2]Joniec-Maciejak I, et al. Octanoic acid prevents reduction of striatal dopamine in the MPTP mouse model of Parkinson's disease. Pharmacol Rep. 2018 Oct;70 (5) :988-992. |[3]Kadota Y, et al. Octanoic acid promotes branched-chain amino acid catabolisms via the inhibition of hepatic branched-chain alpha-keto acid dehydrogenase kinase in rats. Metabolism. 2015 Sep;64 (9) :1157-64. |[4]Leem J, et al. Octanoic acid potentiates glucose-stimulated insulin secretion and expression of glucokinase through the olfactory receptor in pancreatic β-cells. Biochem Biophys Res Commun. 2018 Sep 3;503 (1) :278-284.|[5]Kamata Y, et al. Induction of neurite outgrowth in PC12 cells by the medium-chain fatty acid octanoic acid. Neuroscience. 2007 May 25;146 (3) :1073-81.