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Lacto-N-fucopentaose III

Lacto-N-fucopentaose III (LNFP-III) is an immune modulator. Lacto-N-fucopentaose III reduces the severity of experimental autoimmune encephalomyelitis (EAE) and CNS inflammation[1].

Product Specifications

Product Name Alternative

LNFP-III

UNSPSC

12352005

Target

Aldehyde Dehydrogenase (ALDH) ; Arginase; Indoleamine 2,3-Dioxygenase (IDO)

Type

Natural Products

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/lacto-n-fucopentaose-iii.html

Solubility

10 mM in DMSO

Smiles

OC[C@H]([C@@H]([C@@H]([C@H]1O)O)O)O[C@H]1O[C@H]([C@H](O[C@H]([C@@H]2NC(C)=O)O[C@@H]3[C@H]([C@@H](O[C@@H]([C@@H]3O)CO)O[C@H]([C@H](O)CO)[C@H](O)[C@@H](O)C=O)O)CO)[C@@H]2O[C@H]4[C@H]([C@@H]([C@@H]([C@@H](O4)C)O)O)O

Molecular Formula

C32H55NO25

Molecular Weight

853.77

References & Citations

[1]Zhu B, et al. Immune modulation by Lacto-N-fucopentaose III in experimental autoimmune encephalomyelitis. Clin Immunol. 2012 Mar;142 (3) :351-61.|[2]Brown KA, et al. Lacto-N-fucopentaose-III ameliorates acute and persisting hippocampal synaptic plasticity and transmission deficits in a Gulf War Illness mouse model. Life Sci. 2021 Aug 15;279:119707.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-N11451/Lacto-N-fucopentaose-III-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-N11451/

Scientific Category

Natural Products

Clinical Information

No Development Reported

CAS Number

[25541-09-7]

Available Sizes

Curated Selection

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