P-Tolylmaleimide
P-Tolylmaleimide (compound 9) is a naphthalimide derivative that has cytotoxic effects on cancer cells. p-Tolylmaleimide can arrest the cell cycle of human acute myeloid leukemia cells K562 in the sub-G0/G1 phase and induce apoptosis[1].
Product Specifications
CAS Number
[1631-28-3]
UNSPSC
12352005
Hazard Statement
H302, H315, H318, H335
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/p-tolylmaleimide.html
Purity
98.0
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(C=C1)N(C2=CC=C(C)C=C2)C1=O
Molecular Formula
C11H9NO2
Molecular Weight
187.20
Precautions
H302, H315, H318, H335
References & Citations
[1]Machado KE, et al. Apoptotic events induced by maleimides on human acute leukemia cell lines. Chem Res Toxicol. 2013 Dec 16;26 (12) :1904-16.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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