AA9

AA9 is a potent Transglutaminase 2 (TG2) inhibitor. AA9 strongly impacts HIF-mediated hypoxia in MDA-MB-231 cells[1].

Product Specifications

CAS Number

2134114-20-6

UNSPSC

12352005

Target

Glutaminase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/aa9.html

Smiles

O=C(OCC1=CC=CC=C1)N[C@H](C(N2CCN(C(C3=C4C=CC=CC4=CC=C3)=O)CC2)=O)CCCCNC(C=C)=O

Molecular Formula

C32H36N4O5

Molecular Weight

556.65

References & Citations

[1]Ancona P, et al. Transcriptomics Studies Reveal Functions of Transglutaminase 2 in Breast Cancer Cells Using Membrane Permeable and Impermeable Inhibitors. J Mol Biol. 2024 May 15;436 (10) :168569.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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