1-Methyl-2-nonyl-4 (1H) -quinolone

1-Methyl-2-nonyl-4 (1H) -quinolone, a quinolone alkaloid, is a potent and selective MAO-B (monoamine oxidase) inhibitor. 1-Methyl-2-nonyl-4 (1H) -quinolone exhibites inhibitory activity on leukotriene biosynthesis, with an IC50 of 12.1 μM[1][2].

Product Specifications

CAS Number

[68353-24-2]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Monoamine Oxidase

Type

Natural Products

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/1-methyl-2-nonyl-4-1h-quinolone.html

Solubility

10 mM in DMSO

Smiles

O=C1C=C(CCCCCCCCC)N(C)C2=C1C=CC=C2

Molecular Formula

C19H27NO

Molecular Weight

285.42

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Han XH, et al. Quinolone alkaloids from evodiae fructus and their inhibitory effects on monoamine oxidase. Arch Pharm Res. 2007 Apr;30 (4) :397-401.|[2]Adams M, et al. Inhibition of leukotriene biosynthesis by quinolone alkaloids from the fruits of Evodia rutaecarpa. Planta Med. 2004 Oct;70 (10) :904-8.