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Tacalcitol (Standard)

Tacalcitol (Standard) is the analytical standard of Tacalcitol. This product is intended for research and analytical applications. Tacalcitol (1,24 (R) -Dihydroxyvitamin D3; 1.alpha.,24R-Dihydroxyvitamin D3) can promote normal bone growth by regulating calcium ions. Tacalcitol inhibits cancer cell proliferation and migration. Tacalcitol can be used in the research of inflammation, cancer, and skin diseases.

Product Specifications

CAS Number

57333-96-7

Product Name Alternative

1,24 (R) -Dihydroxyvitamin D3 (Standard) ; 1.alpha.,24R-Dihydroxyvitamin D3 (Standard)

UNSPSC

12352211

Target

Interleukin Related; Reference Standards; VD/VDR

Type

Reference Standards

Related Pathways

Immunology/Inflammation; Others; Vitamin D Related/Nuclear Receptor

Field of Research

Cancer; Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/tacalcitol-standard.html

Smiles

C=C1[C@H](C[C@@H](C/C1=C/C=C2[C@]3([C@@](C)([C@H](CC3)[C@@H](CC[C@H](C(C)C)O)C)CCC/2)[H])O)O

Molecular Formula

C27H44O3

Molecular Weight

416.64

References & Citations

[1]Masuo Morisaki , aoyuki Koizumi , Nobuo Ikekawa et al. Synthesis of active forms of vitamin D. Part IX. Synthesis of 1α,24-dihydroxycholecalciferol. J. Chem. Soc., Perkin Trans. 1, 1975, 1421-1424|[2]Kiyoshige Ochi , Isao Matsunaga , Hiroyuki Nagano et al. Synthetic studies of vitamin D3 analogues from bile acids. Part 3. Syntheses of 1α,25-, 1α,24R-, and 1α,24S-dihydroxycholecalciferols from lithocholic acid and their biological activities. J. Chem. Soc. Perkin Trans.1,1979,165-169|[3]Rostowska-Nadolska et al Vitamin D derivatives: calcitriol and tacalcitol inhibits interleukin-6 and interleukin-8 expression in human nasal polyp fibroblasts. Adv.Med.Sci. (2010) 55 86.|[4]Oiso N, Kawada A.Freckling Promoted by Topical Tacalcitol in a Japanese Boy with Left Eyelid Vitiligo.Pediatr Dermatol. 2011 Oct 20.|[5]Kobayashi T, Okumura H, Azuma Y, Kiyoki M, Matsumoto K, Hashimoto K, Yoshikawa K.1 alpha,24R-dihydroxyvitamin D3 has an ability comparable to that of 1 alpha,25-dihydroxyvitamin D3 to induce keratinocyte differentiation.J Dermatol. 1990 Nov;17 (11) :707-9.|[6]Matsumoto K, Hashimoto K, Kiyoki M, Yamamoto M, Yoshikawa K.Effect of 1,24R-dihydroxyvitamin D3 on the growth of human keratinocytes.J Dermatol. 1990 Feb;17 (2) :97-103.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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