Br-5MP-Propargyl

Br-5MP-Propargyl is the derivative of 5-Methylene pyrrolone (5MP) . 5-Methylene pyrrolones (5MPs) are thiol-specific, reversible bioconjugation reagents for cysteine-specific protein modification, that are commonly used for protein bioconjugation[1]. Br-5MP-Propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Product Specifications

CAS Number

[2468100-37-8]

UNSPSC

12171500

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/br-5mp-propargyl.html

Solubility

10 mM in DMSO

Smiles

O=C(C(Br)=C1)N(CC#C)C1=C

Molecular Formula

C8H6BrNO

Molecular Weight

212.04

References & Citations

[1]Yingqian Zhang, et al. Cysteine-specific protein multi-functionalization and disulfide bridging using 3-bromo-5-methylene pyrrolones. Nat Commun. 2020 Feb 21;11 (1) :1015.