Br-5MP-Propargyl
Br-5MP-Propargyl is the derivative of 5-Methylene pyrrolone (5MP) . 5-Methylene pyrrolones (5MPs) are thiol-specific, reversible bioconjugation reagents for cysteine-specific protein modification, that are commonly used for protein bioconjugation[1]. Br-5MP-Propargyl is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Product Specifications
CAS Number
[2468100-37-8]
UNSPSC
12171500
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/br-5mp-propargyl.html
Solubility
10 mM in DMSO
Smiles
O=C(C(Br)=C1)N(CC#C)C1=C
Molecular Formula
C8H6BrNO
Molecular Weight
212.04
References & Citations
[1]Yingqian Zhang, et al. Cysteine-specific protein multi-functionalization and disulfide bridging using 3-bromo-5-methylene pyrrolones. Nat Commun. 2020 Feb 21;11 (1) :1015.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Curated Selection
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