SY-LB-57

SY-LB-57 is a highly potent bone morphogenetic protein (BMP) receptor signaling agonist. SY-LB-57 can be used in studies of diseases such as fractures and pulmonary arterial hypertension[1].

Product Specifications

CAS Number

[2253719-35-4]

UNSPSC

12352005

Target

TGF-β Receptor

Type

Reference compound

Related Pathways

TGF-beta/Smad

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/sy-lb-57.html

Purity

99.66

Solubility

DMSO : 16.67 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

COC1=CC2=C(NC(C3=NC4=CC=CC=C4N3)=C2)C=C1

Molecular Formula

C16H13N3O

Molecular Weight

263.29

References & Citations

[1]Sheyda Najafi, et al. Discovery of a novel class of benzimidazoles as highly effective agonists of bone morphogenetic protein (BMP) receptor signaling. Sci Rep. 2022 Jul 15;12 (1) :12146.