Milbemycin A4 (Standard)
Product Specifications
UNSPSC Description
Milbemycin A4 (Standard) is the analytical standard of Milbemycin A4. This product is intended for research and analytical applications. Milbemycin A4 inhibits P-glycoprotein activity, and reverses multidrug resistance of tumor cells. Milbemycins are a family of macrolide antibiotics with insecticidal and acaricidal activity[1]sup>[2].
Target Antigen
Antibiotic; P-glycoprotein
Type
Reference Standards
Related Pathways
Anti-infection;Membrane Transporter/Ion Channel
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/milbemycin-a4-standard.html
Smiles
O=C1[C@]2([H])C=C(C)[C@@H](O)[C@]3([H])[C@@]2(O)/C(CO3)=C/C=C/[C@H](C)C/C(C)=C/C[C@]4([H])C[C@@](O1)([H])C[C@@]5(O[C@H](CC)[C@@H](C)CC5)O4
Molecular Weight
542.70
References & Citations
[1]Li J, et al. Isolation and identification of new macrocyclic lactones from a genetically engineered strain Streptomyces bingchenggensis BCJ60. J Antibiot (Tokyo). 2017 Mar;70(3):297-300.|[2]Takiguchi Y, et al. Milbemycins, a new family of macrolide antibiotics: fermentation, isolation and physico-chemical properties. J Antibiot (Tokyo). 1980 Oct;33(10):1120-7.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-126906R/Milbemycin-A4-Standard-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-126906R/
CAS Number
51596-11-3
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