Milbemycin A4 (Standard)

Milbemycin A4 (Standard) is the analytical standard of Milbemycin A4. This product is intended for research and analytical applications. Milbemycin A4 inhibits P-glycoprotein activity, and reverses multidrug resistance of tumor cells. Milbemycins are a family of macrolide antibiotics with insecticidal and acaricidal activity[1]sup>[2].

Product Specifications

CAS Number

[51596-11-3]

UNSPSC

12352005

Target

Antibiotic; P-glycoprotein; Reference Standards

Type

Reference Standards

Related Pathways

Anti-infection; Membrane Transporter/Ion Channel; Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/milbemycin-a4-standard.html

Smiles

O=C1[C@]2([H])C=C(C)[C@@H](O)[C@]3([H])[C@@]2(O)/C(CO3)=C/C=C/[C@H](C)C/C(C)=C/C[C@]4([H])C[C@@](O1)([H])C[C@@]5(O[C@H](CC)[C@@H](C)CC5)O4

Molecular Formula

C32H46O7

Molecular Weight

542.70

References & Citations

[1]Li J, et al. Isolation and identification of new macrocyclic lactones from a genetically engineered strain Streptomyces bingchenggensis BCJ60. J Antibiot (Tokyo) . 2017 Mar;70 (3) :297-300.|[2]Takiguchi Y, et al. Milbemycins, a new family of macrolide antibiotics: fermentation, isolation and physico-chemical properties. J Antibiot (Tokyo) . 1980 Oct;33 (10) :1120-7.