Tusamitamab

Tusamitamab is an IgG1 monoclonal antibody that targets CEACAM5. Tusamitamab can be used to synthesize ADC Tusamitamab ravtansine (SAR408701) (HY-P99542) [1].

Product Specifications

CAS Number

[2349294-95-5]

UNSPSC

12352203

Target

ADC Antibody; Transmembrane Glycoprotein

Type

Inhibitory Antibodies

Related Pathways

Antibody-drug Conjugate/ADC Related; Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tusamitamab.html

Purity

99.81

Solubility

H2O

Smiles

[Tusamitamab]

Molecular Weight

(144.76 kDa)

References & Citations

[1]Clemence Pouzin, et al. Covariate analysis of tusamitamab ravtansine, a DM4 anti-CEACAM5 antibody-drug conjugate, based on first-in-human study. CPT Pharmacometrics Syst Pharmacol. 2022 Mar;11 (3) :384-394.